Thyroid Hormones For Fat Loss In Women

A 40 year old woman claimed to be active in sport. She started to join swimming competition when she was a kid and eats healthily on organic foods. She however, admitted her big appetite of eating after training is helpless. She never really counts calories but fortunately, with the sports she does, she never has an issue with weight or body fat.

As years pass by, she can�t keep off the fat and she took T4 wrongly. The overdosed of T4 has led her to bulking. The heart rate began to increase but the fat loss program is effective although it caused another trouble. And then she tried T3, but this time, with a proper dosage of 100 mcg/day.

But another problem occurred as the heart rate affects her training and the fat loss program is no longer effective. She supported her training with fat loss supplement including thyroid hormone.

But another question comes to mind, is it effective? And what about the difference between T3 and T4?

This woman�s case is a genetically gifted one. She is able to stay slim while having big appetite. Not all people are able to maintain a lean body while eating a lot and only rely on training. At the age of 40, the case is different. Our body will experience a certain degrade and getting back a lean body might not be easy like when you are 20. Hence, calories are the things to avoid if you want to lose some fat.

Fat loss supplements may be effective to some people. It works by reducing your appetite released by the chemical substance in the supplement. In return, it raises the metabolic rate and the process.

This significant loss of appetite, causes an individual to eat less � and lose fat. The supplement products generally work like this.

    The T3 effect

When you take T3, the food you consume has to �work� to match the calorie burning rate. This way, you don�t lose fat.

    The T4 effect

T4 is rather extreme or stronger than T3. And you will have fat loss.

Thyroid hormones: don�t overdose it
It is important to note that thyroid hormones must not be abused. Once overdose, it is hard to actually recover.

The powder is not recommended however, if an individual needs to take it, it must be in a very small dose and prescribed by a nutritionist if possible because there has to be an exact 100% of certainty.

Some women have been reportedly gain weight and it is a noticeable sign that they have overdosed the thyroid.

Even when they have struggled, they can�t figure out why. Thyroid impair is caused by the wrong dosage and it affects the slowing down of your rate.

Recommended intake of thyroid hormone:

    The best dosage is less than 50 mcg/day for T3.  You need to divide it to 3 doses.
    The best dosage T4 is less than 200 mcg/day.

T4 vs T3
T4 has a longer effect when used than T3. Hence, it is preferable to take T4. However, for some individuals, T3 is proven to be more effective. People find that T3 is more convenient in terms of conversion.

Thyroid affects most women
There are many reasons why women have thyroid issues and here are some of the factors
- Pregnancy
- PMS
- And per menopause

The calorie intake must be well monitored. The dose of thyroid hormone needs to be a certain number allowed because it will affect the metabolic rate.

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T3 for Accelerating Weight Loss

T3 (Trijodthyronin, Cytomel) - a thyroid hormone. It is related to and even more important than the other but more popular thyroid hormone, T4 or thyroxine.

Thyroxine is the precursor of T4 and the production of both hormones is signaled in the thyroid gland by TSH or thyroid stimulating hormone.

Thyroid stimulating hormone is released from the pituitary gland and forms a feedback loop with both T3 and T4. Therefore, when the plasma levels of the thyroid hormone falls, TSH production is increased and when the thyroid hormones rise above their normal plasma levels, TSH production is reduced.


What T3 Does and How It Works

The biological effects of T3 are extensive and the hormone contributes to almost all the physiological processes in the human body. For example, T3 affects heart rate, the rate of metabolism, body temperature and growth rate.

In the blood, T3 binds to specific types of carrier proteins: serum albumin (with low affinity) and thyroid-binding globulin (with high affinity).

These molecules increase the stability and longevity of T3 but impede the uptake of the hormone by tissues. For T3 to pass through tissues, it must shed its carrier protein.

To produce its biological effects, T3 binds to thyroid receptors in tissues. In addition, because it is fat-soluble, it can cross into cells through their phospholipid layers.

T3 can be found in most tissues although it is notably absent in the tissues of the testes and spleen.

Its overall effect depends on the part of the body where it acts. However, T3 generally increases the basal metabolic rate.

When T3 increases the rate of metabolism, it does the following:

    Increase the amount of oxygen and energy used up by the body
    Increase the amount of calories required for normal body processes even when the muscles are rested
    Increase the population of sodium/potassium/ATPase, the primary energy-generating complex in the body
    Increase the use and breakdown of many nutrient macromolecules produced in the body

On proteins, T3 increases the rate of their production and degradation by increasing the amount of the enzymes, RNA polymerase I and II.

For carbohydrates, T3 increases gluconeogenesis. Gluconeogenesis is the production of glucose from stored glycogen. This effect is mediated by beta adrenergic receptors. By acting on beta adrenergic receptors, T3 can increase heart rate and pulse rate. Specifically, T3 increases systolic blood pressure but decreases diastolic blood pressure.

On lipids, T3 increases the rate of lipolysis. Specifically, it drives the breakdown of cholesterol and increases the number of LDL receptors.

In the brain, T3 increases the production of certain neurotransmitters especially serotonin.

The positive effect of T3 on serotonin is the reason it is now recommended (along with SSRIs or selective serotonin receptor inhibitors) in the treatment of drug-resistance and recurring depression and bipolar disorders. Different studies have established that long-term supplementation with T3 significantly improves the symptoms of (and may even �cure�) these psychological disorders.

T3 (or any of its prodrugs) is also used as a fat loss supplement. It has been proven to increase the metabolism of fatty acid and the breakdown of fat stored in adipose tissue

How T3 Can Promote Weight Loss

The only mechanism by which T3 promotes weight loss is by increasing metabolic rate.

Although it is a one-trick weight loss solution, that one trick is pretty remarkable. T3 increases basal metabolic rate by increasing the rate at which the body breaks down all food groups. It unlocks significant energy for the body to use, and it can produce very dramatic results especially in overweight people with diagnosed or silent hypothyroidism.

When the amount of thyroid hormones produced in the body falls, the rate of metabolism falls with it. In this regard, the amount of circulating T3 is more important than that of T4.

Because of the reduced metabolic rate, low thyroid functioning results in difficulty in reducing body weight. When overweight individuals adopt healthy, low caloric diets and take up regular exercise but still cannot shed weight, the most likely reason is low metabolic rate caused by low T3 levels.

Even a 10% reduction in metabolic rate can make weight loss very difficult. However, available clinical data suggest that most people who find it difficult to lose weight have 15 � 40% reduction in metabolic rate.

For this group of people, T3 is the magic remedy for losing weight.

The ability of T3 to prompting weight loss does not really depend on adopting a low caloric diet. In fact, the usual response to a low-carbohydrate diet is a reduction in the body�s metabolic rate. By supplementing with T3, the body keeps up a high rate of metabolism even with the amount of calories in the diet is reduced.

Exercise, on the other hand, has a more significant effect on the result of T3 supplementation in weight loss. In fact, T3 increases the amount of available energy, and practically encourages the user to exercise.

Unlike stimulants like caffeine and synephrine, T3 increases the rate of metabolism without such side effects as jitters. It does not make the user �hyper�. Instead, it simply energizes the user without the crash that comes from overstimulation with stimulants.

When taking T3 for weight loss, the aim is to increase the levels of T3 to the edge of the upper limit while not stepping over and setting off hyperthyroidism.

To do that, it is important to closely monitor the plasma levels of T3 while taking the supplement.

Where this is not possible, clear signs of hyperthyroidism such as irregular, rapid heartbeats should be the indication to stop T3 supplementation.

In most cases of abnormal weight gain even in the face of dieting and exercise, there is an impairment in the enzymes responsible for converting T4 to T3. Since most of the circulating T3 in the body comes from T4, such impairment makes it important to find another source of T3. This can be done through drugs and supplements that increase T3 levels.

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